Fri Jul 11 2025

120 articles - From Friday Jul 04 2025 to Friday Jul 11 2025

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

J Neurogastroenterol Motil

Validation of Lyon 2.0 Gastroesophageal Reflux Disease Consensus: Limited Clinical Utility of Mean Nocturnal Basal Impedance in Koreans.

MNBI significantly correlated with AET and LA grades, highlighting its diagnostic value in Korean GERD patients. However, regional variations suggest higher MNBI thresholds than Lyon 2.0 recommendations, warranting further studies to refine criteria for Asian populations.

Pubmed   Journal   ReadQx 


Meta-analysis

meta-analyses and systematic reviews

Aliment Pharmacol Ther

Systematic Review: Incidence of Liver-Related Events in People Living With Hepatitis Delta Virus.

The number of studies describing the incidence of liver-related outcomes among people with HDV remains limited. Quantifying incidence of liver-related events can improve our understanding of disease progression and inform potential treatment strategies.

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Clin Gastroenterol Hepatol

The Affordable Care Act Improves Access, Survival, and Racial Disparities of Patients with Liver Disease: A Systematic Review.

The ACA, particularly ME, improved access, survival, and equity among Medicaid-eligible adults with CLD. Individuals in NME states would likely benefit from expansion, and future liver health policy should consider these findings to reduce disparities.

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Endosc Int Open

Bowel preparation assessment using artificial intelligence: Systematic review.

AI-BPS can standardize and outperform human bowel preparation evaluation by better correlating with expert BBPS ratings, AMR, ADR, and PDR. Further research following recommended reporting guidelines is needed to allow for cross-study comparisons and meta-analysis, which was not possible in this study due to heterogonous study design and reporting metrics.

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Effectiveness and safety of endoscopic submucosal dissection for residual or recurrent colorectal neoplasia: Meta-analysis.

This meta-analysis suggests that ESD is effective and safe for treating residual or recurrent colorectal neoplasia after previous resection, with further prospective validation studies needed to compare ESD with other endoscopic resection methods and surgery in this context.

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Gastroesophageal reflux disease over time in endoscopic versus surgical myotomy for treatment of achalasia: Systematic review and meta-analysis.

A higher rate of early GERD is observed in POEM compared with HMF, with the difference waning over time and reaching equivalence after 12 months, despite a higher rate of GAST in the endoscopic group. POEM also exhibited effectiveness and safety comparable to the surgical approach.

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Gastrointest Endosc

Postprocedural cholecystitis following covered self-expandable metal stent placement in patients with distal malignant biliary obstruction: a systematic review and meta-analysis.

Our study demonstrated higher rates of post-procedural cholecystitis following ERCP with CSEMS placement compared to USEMS. These findings highlight the importance of careful stent selection, particularly in patients with gallbladder in-situ, to optimize patient care, reduce adverse events and prevent delays in oncologic management.

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J Neurogastroenterol Motil

Diagnostic Criteria and Symptom Profiles in Adult Idiopathic Gastroparesis: A Systematic Review.

The findings highlight the inherent diagnostic challenges and underscores the need for confirming delayed gastric emptying to clinch an accurate diagnosis of gastroparesis. Future research should focus on developing consistent diagnostic criteria across diverse populations to improve the diagnosis and management of idiopathic gastroparesis.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Aliment Pharmacol Ther

Effectiveness and Safety of First-Line Non-Bismuth Quadruple Concomitant Therapy Versus Single-Capsule Bismuth Quadruple Therapy.

Sc-BQT is more effective, better tolerated, and more broadly applicable than 14-day CT. Both regimens achieved ≥ 90% success, but Sc-BQT's stewardship-friendly profile further supports its use as first-line therapy for H. pylori eradication.

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MELD 3.0 Improves Risk Stratification and Mortality Prediction in Hepatorenal Syndrome-Acute Kidney Injury: A Multicentre Study.

This is the first large-scale study to validate MELD 3.0 in HRS-AKI. By offering enhanced discrimination and clinically meaningful reclassification, MELD 3.0 provides a more refined tool for early risk stratification, with potential to guide timely intervention, inform transplant decisions and improve personalized care in this critically ill population.

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Am J Gastroenterol

Early Improvement of Mental Health is Associated with Long-term Disease Remission in Ulcerative Colitis.

Early mental health improvements independently predicted long-term disease remission. Integrating mental health assessments into UC management strategies may provide valuable insights beyond physical symptoms.

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Fecal Immunochemical Test (FIT) Completion by Instruction Type: A Randomized Clinical Trial Comparing QR-Code linked Video to Pictorial Instructions.

Providing QR-code based education offers a promising format for delivering low literacy instructions, which might be a practical strategy to improve FIT completion for CRC screening.

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Local post-procedural cryoprevention significantly reduces the incidence of post-ERCP pancreatitis: a multicenter randomized controlled trial.

Cryoprevention using ice water significantly reduced PEP incidence, demonstrating a safe, effective, and low-cost strategy. This approach offers a practical alternative, where NSAID use is limited.

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Microbial Dysbiosis in the Urinary Microbiome of Patients with Cirrhosis.

Reduced microbial diversity and lower Streptococcus abundance in patients with cirrhosis might help to explain their heightened susceptibility to UTIs.

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Post-Colonoscopy Colorectal Cancer in Fecal Immunochemical Test-Positive Individuals: Prevalence, Predictors, and Root-Cause Analysis in a Nationwide Cohort.

Among FIT-positive individuals, the PCCRC-3y rate was 6.4%, with missed lesions and incomplete resection as key contributors. These findings provide useful information on quality metrics in FIT-based CRC screening programs.

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Safety of early oral refeeding in patients with chronic pancreatitis after extracorporeal shock wave lithotripsy of pancreatic stone (SHEEL): A multicenter randomized controlled trial.

Early oral refeeding in patients after ESWL was safe and did not increase the incidence of post-ESWL pancreatitis. This was also associated with reduced abdominal discomfort and hunger.

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Clin Gastroenterol Hepatol

An International Multicenter Study of Native and Immigrant South Asian Crohn's Disease.

Our international, multicenter study identified both commonalities as well as unique differences in disease phenotype, behavior, serological patterns and environmental factors by geography and immigrant status. We highlight the importance of changing environment on CD phenotypic expression.

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Efficacy of 6-mm and 8-mm transjugular intrahepatic portosystemic shunt for variceal bleeding: a randomized controlled trial.

Among this cohort of patients with cirrhosis who are receiving TIPS for the secondary prevention of variceal bleeding, the use of 6-mm stents results in a higher rate of rebleeding but has similar survival and a significantly lower risk of OHE compared to 8-mm stents.

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Efficacy of etrasimod in ulcerative colitis: analysis of ELEVATE UC 52 and ELEVATE UC 12 by baseline endoscopic severity.

Etrasimod demonstrated significant induction and maintenance efficacy over placebo in both moderate and severe endoscopic disease. Response to etrasimod in patients with severe endoscopic disease may continue to improve beyond 12-week induction therapy (ClinicalTrials.gov NCT03945188; NCT03996369).

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Liver Failure, Hepatic Encephalopathy, and Infection Contribute to Mortality Risk in a Global Cirrhosis Cohort.

Cutoffs associated with mortality are admission bilirubin >7.5 mg/dl, INR >1.5, creatinine > 1.5 mg/dL; MELD >27 and MELD3.0 >28. Liver failure may therefore be identified by the serum bilirubin>7.5mg/dL and INR>1.5, with hepatic encephalopathy and admission infections as contributors towards mortality.

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Nasal CPAP to Reduce Hypoxia in Patients with Obesity Undergoing Sedated Upper GI Endoscopy: A Prospective Randomized Trial.

nCPAP significantly reduces hypoxia risk and stabilizes oxygen saturation in patients with obesity undergoing sedated upper GI endoscopy, supporting its routine use in these high-risk patients. Further studies should explore its broader clinical application.

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Risk factors of metabolic dysfunction-associated steatotic liver disease in a cohort of patients with chronic hepatitis B.

In this large European cohort, MASLD and fibrosis were highly prevalent among CHB, while MASLD aggravated liver fibrosis. Though screening strategies remain inconsistent, ferritin levels, increased BMI and T2DM may inform on the presence of MASLD. Biomarkers showed modest performance in predicting fibrosis.

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Endosc Int Open

Bridging the gap in gastrointestinal healthcare in a resource-limited setup: Feasibility study of weekend endoscopy services in Southwest Ethiopia.

The study demonstrates the feasibility and effectiveness of a weekend outreach endoscopy service led by a trained gastroenterologist in a rural Ethiopian setting. The unexpectedly high prevalence of upper gastrointestinal disorders, including cancers, and the long duration of symptoms before endoscopy likely reflect delayed diagnoses due to limited access to endoscopy. Moreover, presence of alarm symptoms predicted major endoscopic findings. Expanding endoscopy services, increasing public awareness, and further research into risk factors and preventive strategies for these diseases are recommended.

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Comparing ChatGPT3.5 and Bard recommendations for colonoscopy intervals: Bridging the gap in healthcare settings.

This study highlights the limitations of freely available LLMs in assisting colonoscopy screening recommendations. Although the potential of freely available LLMs to offer uniformity is significant, the low accuracy, as noted, excludes their use as the sole agent in providing recommendations.

Pubmed   Journal   ReadQx   PMC

Diagnostic performance and agreement of auditors for evaluation of computer-aided optical polyp diagnosis: Prospective study.

Expert audit for evaluating CADx resulted in high sensitivity and interobserver agreement for high-confidence adenomas. Audit by two experts, with a third expert for arbitration, permitted audit of al polyps and effective assessment of CADx within clinical studies.

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Does development of submucosal dissection models influence quality of training? Comparison of existing models.

Ex-vivo models are good models for learning ESD skills. The bovine colon model seems to be the most discriminating. Synthetic models should be reserved for novices.

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Endoscopic mucosal resection for Barrett's neoplasia: Long-term outcomes from the largest Canadian single-center experience.

While the success rate of EMR for BE is excellent, this study highlights substantial long-term risk of neoplastic recurrence, underscoring the need for indefinite surveillance for patients who had HGD or EAC.

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Endoscopic retrograde cholangiopancreatography services in Sudan during wartime: Innovations in crisis.

Development of a local scoring system for trainee assessment after 50 supervised procedures aims to establish a sustainable ERCP fellowship program, addressing the shortage of specialists. These efforts highlight resilience and innovation in delivering ERCP services during conflict.

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Ex vivo evaluation of a novel through-the-scope traction device for endoscopic submucosal dissection.

TRACMOTION significantly improves the efficiency of ESD, reducing procedure time and complication rates. This traction device could potentially facilitate broader adoption of ESD in clinical practice. However, further research in human trials is necessary to validate these findings.

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Feasibility of real-time artificial intelligence-assisted anatomical structure recognition during endoscopic submucosal dissection.

In this proof-of-concept study, feasibility of a real-time AI algorithm for anatomical structure delineation and orientation support during ESD was evaluated. The application proved safe and appropriate for routine procedures in humans. Further studies are needed to elucidate a potential clinical benefit of this new technology.

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Implementing endoscopy video recording in routine clinical practice: Strategies from three tertiary care centers.

By describing successful strategies, we aim to inspire gastroenterology divisions worldwide to adapt routine video recording for endoscopy procedures, thereby increasing the volume and diversity of datasets necessary for developing clinically impactful AI applications.

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Mobile health technology in quality assessment of pediatric ileocolonoscopy: Results of the SIGENP national program.

mHealth was effective in assessing the quality of pediatric endoscopy. Levels of bowel preparation, sedation, TI intubation rate, and safety were adequate in Italy, whereas waiting time and post-procedure communication seemed to be the most critical areas of concern.

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Positive provocative testing and symptom evaluation for detecting upper extremity repetitive use injuries among endoscopists.

Our study found a high prevalence of repetitive use injury symptoms among endoscopists, corroborated by objective physical examination and testing.

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Radiofrequency ablation: Solution for a long-time therapeutic dilemma of chronic radiation proctitis?

These data indicate that RFA is a highly effective and safe treatment option for chronic radiation proctitis, providing excellent long-term results.

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Retrospective study comparing rectal endoscopic submucosal dissection with and without Foley catheter drainage tube placement.

Foley catheter placement notably improved efficiency of rectal ESD performed by novice endoscopists, particularly by increasing dissection speed. This technique may contribute to safer and more effective ESD. However, larger studies are needed to confirm these findings and further assess their benefits.

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Endoscopy

Devices and techniques for bariatric and metabolic endoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Technical and Technology Review.

The paper emphasizes the necessity for additional high quality randomized controlled trials and long-term outcome data to better define the role of these therapies within obesity treatment protocols. Overall, this review serves as an authoritative resource for endoscopists, bariatric specialists, and the wider healthcare community involved in obesity care, promoting best practices and guiding the appropriate implementation of EBMTs in clinical settings.

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Multicenter validation of a cholangioscopy artificial intelligence for evaluation of biliary tract disease.

A previously developed cholangioscopy AI was found to continually outperform standard ERCP sampling modalities for accurate identification of malignancy without additional retraining in a multicenter validation cohort.

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Two-sample Fecal Immunochemical Testing as a Tool to avert Colonoscopy in Symptomatic Patients - A prospective multicenter cohort study.

Two-sample FIT can achieve a NPV of 99.3% for IBD and 95.6% for AN with a sensitivity of 83.3% and 71.7% respectively. Concordant negative results were found in 71.1%. However, 28.3% of AN was still missed. Therefore, two-sample FIT may play a role in determining the need for colonoscopy in symptomatic patients, but it misses too many lesions to be used as the sole determinant to avert colonoscopy.

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Gastroenterology

Chemical perturbations impacting histone acetylation govern colorectal cancer differentiation.

Our findings establish histone acetylation as a chemically targetable mechanism governing CRC cell fate and demonstrate that epigenetic reprogramming can be leveraged as a therapeutic strategy. By identifying HDAC½ inhibition as a driver of differentiation and revealing H3K27ac as a key regulatory mark, this study provides a framework for targeting chromatin-modifying enzymes to counteract CRC plasticity and improve treatment outcomes.

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Dietary Patterns and Incident Chronic Constipation in Three Prospective Cohorts of Middle- and Older-aged Adults.

Our findings suggest that dietary patterns emphasizing plant-based foods and healthy fats may protect against constipation, informing future dietary interventions and treatments for chronic constipation.

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Peyer's patch B cells sample transglutaminase-gluten complexes and drive celiac disease autoimmunity.

The model supports a mechanism where TG2-gluten complexes formed in the gut lumen are taken up by TG2-specific B cells in GALT. We propose that this pathway plays an important role in driving the anti-TG2 IgA autoantibody response in celiac disease patients. The model provides a platform to explore novel approaches for celiac disease therapies.

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RISK OF PANCREATIC CANCER IN GLYCEMICALLY DEFINED NEW-ONSET DIABETES: A PROSPECTIVE COHORT STUDY.

Glycemically defined new-onset diabetes, identifiable in real-time using active surveillance of electronic health records, is associated with a high 3-year incidence of pancreatic cancer with marked racial/ethnic differences. Longer term risk needs further study.

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Gastrointest Endosc

Clinical Characteristics Analysis of Anorectal Function Changes After Endoscopic Submucosal Dissection for Rectal Lesions.

The occurrence of anorectal symptoms following rectal ESD is closely related to the location and size of the lesion. The psychological and quality-of-life impairments caused by these symptoms are primarily short-term and can gradually recover over time.

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Endoscopic Submucosal Resection Using a Ligation Band without Injection for Rectal Neuroendocrine Tumors.

ESMR-L without injection can be simpler and more effective for small rectal NETs than ESMR-L with injection.

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Feasibility and safety of endoscopic submucosal dissection for the anal canal lesions.

The favorable short- and long-term outcomes indicate ESD is a safe, effective, and attractive therapeutic modality for ACLs. A multicenter and prospective study should be conducted to validate this technology.

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Risk factors of bleeding ulceration after argon plasma coagulation in patients with radiation-associated vascular ectasias.

Rectal EQD2 D10cc ≥70 Gy is an independent risk factor for bleeding ulceration after APC for RAVE. In multidisciplinary management involving therapeutic radiologists, endoscopists may consider non-ablative treatment instead of APC in patients with rectal EQD2 D10cc ≥70 Gy.

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Gut

Crohn's disease and ulcerative colitis exhibit prediagnostic antibody signatures with shared and divergent changes towards disease onset.

This study is the first comprehensive high-resolution analysis of the exact antigenic nature of systemic antibody responses during the transition from prediagnostic to established IBD. The antibody signatures we found may represent a route to developing biomarkers that identify individuals at high risk of developing disease.

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Hepatology

Aging disrupts hepatocyte zonation homeostasis in mice and humans.

These findings reveal that aging causes loss of distinct hepatic zonation and alters intercellular communication through widespread transcriptional and architectural remodeling of liver cell types. The emergence of bi-zonal hepatocytes and expansion of hepatic zones in aged livers represent key hallmarks of hepatic aging. Our study provides new insights into mechanisms of liver aging and may inform therapeutic strategies targeting age-associated liver dysfunction.

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Biliary YB-1/GLI2 axis facilitates ductular reaction and promotes hepatic stellate cell activation via SPP1/Integrin αvβ1 signaling during liver fibrogenesis.

YB-1/GLI2 axis promotes DRC proliferation and SPP1 secretion, which facilitates HSC activation through integrin αvβ1 receptors. This study highlights the YB-1/GLI2/SPP1 signaling pathway as a potential target for therapeutic intervention in liver fibrosis.

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Environmental Risk Factors for Liver Cancer.

A number of other environmental factors have been studied for an association with liver cancers, such as air pollution, per- and polyfluoroalkyl substances, cyanobacteria, pesticides, aristolochic acid, polycyclic aromatic hydrocarbons, asbestos, arsenic, and organic solvents, however limited evidence exists for these exposures. It is the goal of this review article to examine what is currently known about environmental risk factors and liver cancer and suggest which ones should have the highest priority for further research.

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Liver resection with and without vascular resection versus transplantation for de novo perihilar cholangiocarcinoma.

Both LR and RT+LT achieve excellent oncological outcomes in selected de novo pCCA patients. Key challenges remain dropouts during neoadjuvant therapy in patients planned for LT and high perioperative mortality for patients undergoing LR. OS doubles in LR+VR patients compared to dropouts, supporting LR+VR as a viable option for LT-ineligible patients. Appropriate patient selection is crucial, as those not undergoing surgery suffer from a dismal prognosis.

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Prognostic significance of mild ascites in patients with cirrhosis.

Grade 1 (mild or subclinical) ascites is associated with poorer survival compared to no ascites and represents an intermediate prognostic stage between compensated and decompensated cirrhosis.

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Salivary microbiome and serum metabolomics add to clinical biomarkers to predict 6-month hospitalizations in a multi-center cirrhosis outpatient cohort.

In a multi-center North American outpatient cirrhosis cohort with controlled etiologies, serum metabolomics and salivary microbiome add to clinical variables to prognosticate 6-month hospitalization.

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J Hepatol

Prevalence, severity and determinants of steatotic liver disease among individuals with metabolic and alcohol risk from the community.

Among individuals with cardiometabolic and/or alcohol risk factors, 70% had SLD, 10% had elevated liver stiffness, and 2% had biopsy-confirmed advanced liver fibrosis. NCT03308916 IMPACT AND IMPLICATIONS Steatotic liver disease (SLD) remains underdiagnosed in the general population. This study provides new population-based data on its prevalence and severity among individuals with metabolic and/or alcohol-related risk. These findings are relevant to clinicians, researchers, and public health planners, as prevalence data are essential to inform evolving screening strategies. Methodological limitations, including the cross-sectional design and limited generalizability, should be considered when interpreting the results.

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Somatic loss-of-function mutations in CIDEB reduce hepatic steatosis by increasing lipolysis and fatty acid oxidation.

Cideb deletion is more protective in some types of fatty liver disease. β-oxidation is an important component of the Cideb protective mechanism. CIDEB inhibition represents a promising approach, and somatic mutations in CIDEB might predict the patient populations that might benefit the most. Impact and implications It is not clear why somatic and germline CIDEB mutations are protective in MASLD. Cideb mutations are predominantly loss of function, and Cideb-deficient clones selectively expand in specific dietary contexts such as CDA-HFD-induced MASLD. Consistently, liver-wide deletion of Cideb ameliorates MASLD most profoundly after CDA-HFD feeding. Mechanistically, Cideb deficiency enhances hepatic fatty acid β-oxidation via ATGL and PPARα activation. These findings suggest that CIDEB inhibition might be most effective in patients with the subtypes of MASLD that promote the expansion of CIDEB mutant clones.

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Spatiotemporal liver dynamics shape hepatocellular heterogeneity and impact in vivo gene engineering.

These insights into spatiotemporal hepatocyte dynamics enhance our understanding of liver biology and have important implications for therapeutic strategies. Impact and implications We provide new insights into the spatiotemporal dynamics of the mouse liver during postnatal growth, highlighting both proliferative and transcriptomic heterogeneity among hepatocytes and their impact on the efficiency and distribution of in vivo lentiviral gene delivery and targeted gene editing. Understanding and manipulating the biological processes behind this heterogeneity can enhance gene transfer outcomes. We report that not al hepatocytes contribute equally to liver growth, indicating that effectively targeting clonogenic hepatocytes in the newborn liver is crucial for the long-term maintenance of therapeutic genetic modifications. Furthermore, this phenomenon can be leveraged to expand the pool of genetically corrected cells, as illustrated here by a targeted gene editing strategy. Finally, we reveal the existence of a tissue niche that supports the proliferation of both clonogenic hepatocytes and hematopoietic progenitors in neonatal livers. Gaining a deeper understanding of this niche and its signals could be beneficial for regenerative purposes.

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J Neurogastroenterol Motil

Assessing Treatment Outcomes in Achalasia Using 4-Dimensional High-resolution Impedance Manometry.

IBP and clearance ratio help to identify abnormal barium retention in patients after treatment. 4D manometry can be an alternative or complementary approach to characterize and assess treatment response of Achalasia, in additional to TBE or functional lumen imaging probe.

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Assessment of Small Bowel Motility Using Cine-magnetic Resonance Imaging in Patients Suspected With Chronic Intestinal Pseudo-obstruction.

Cine-MRI is useful in assessing SB motility that cannot be detected on CT. Its usefulness extends to aiding surgical decision-making, particularly in differentiating between FHAM and CIPO.

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Association Between Psychological Burden and Unexplained High Upper Esophageal Sphincter Basal Pressure.

Elevated UES basal pressure is more frequently seen in symptomatic patients with high esophageal hypervigilance and anxiety. When encountering patients with unexplained high UES basal pressure, psychological burden may play a potential role in these cases.

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Clinical Characteristics and Associated Factors in Mexican Patients With Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis Syndrome.

This study presents the first detailed analysis of CVS and CHS in the Mexican population, revealing some demographic and clinical differences from global data. These findings highlight the importance of developing region-specific guidelines for diagnosing and managing these conditions, especially given Mexico's changing cannabis policies.

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Clinical Relevance of Gastric Emptying Time in Functional Dyspepsia.

GET did not significantly differ among FD patients or its subtypes, despite a lower gastric retention rate in FD patients.

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Long-term Effects of Potassium-competitive Acid Blockers and Proton Pump Inhibitors on Gastrin, Gastric Emptying Rate, and Small Intestinal Microbiota in Rats.

Long-term administration of P-CABs and PPIs altered gastrin levels, GE, and gut microbiota. Therefore, the acid suppression-related adverse effects of P-CABs and PPIs are expected to be similar.

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Real-world Application of the Chicago Classification Version 4.0 for Esophageal Manometry: Asian Multicenter Study.

We observed heterogeneity among centers in the application of CC v4.0 protocol. To increase inter-center reliability and minimize diagnostic ambiguity, efforts should continue toward the practical clinical application of standard protocols.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Aliment Pharmacol Ther

Editorial: Bridging the Gap Between Evidence and Practice in Hepatitis B Virus-Related Hepatocellular Carcinoma Prevention.

Pubmed   Journal   ReadQx 

Editorial: JAK to JAK-Navigating Intraclass JAK Inhibitor Switching in Inflammatory Bowel Disease.

Pubmed   Journal   ReadQx 

Endosc Int Open

Between hype and hard evidence: Are large language models ready for implementation in surveillance colonoscopy?

Pubmed   Journal   ReadQx   PMC

Gastroenterology

Endoscopic Surveillance for Non-Dysplastic Barrett's Esophagus: Are We Violating "Primum Non Nocere"?

Pubmed   Journal   ReadQx 

J Hepatol

Mechanisms and Management of Graft In- and Out-flow in Liver Transplantation: A Narrative Review of the Literature and Guide for Interventional Management.

Overall, an understanding of complex hepatic vascular regulation is essential to optimizing liver graft function in transplantation. This review may help surgeons as they continue to strive for improved access to transplantation across the world.

Pubmed   Journal   ReadQx 

Staging decompensated cirrhosis: Lumping, splitting, or just rearranging the deck chairs on the Titanic?

Pubmed   Journal   ReadQx 

J Neurogastroenterol Motil

"Ulcerative Colitis and Irritable Bowel Syndrome Are Diagonally Opposite." Missing the Trees for the Woods.

Pubmed   Journal   ReadQx 

Does Mean Nocturnal Baseline Impedance Play a Role in Managing Gastroesophageal Reflux Disease?

Pubmed   Journal   ReadQx 

From Morphology to Motion: Cine-magnetic Resonance Imaging in the Functional Assessment of Pseudo-obstruction.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Am J Gastroenterol

A splenic artery aneurysm masquerading as a gastric subepithelial tumor.

Pubmed   Journal   ReadQx 

Ileal Perforation Caused by Ingested Toothpicks.

Pubmed   Journal   ReadQx 

Potassium Chloride-induced Acute hemorrhagic Erosive Gastropathy.

Pubmed   Journal   ReadQx 

Reflux Hypersensitivity or Functional Heartburn Can Be the Cause of Persistent Symptoms in Patients With Confirmed GERD Refractory to PPI Treatment.

Pubmed   Journal   ReadQx 

Response to Zhong et al and Xu et al.

Pubmed   Journal   ReadQx 

Clin Gastroenterol Hepatol

One-Year Comparative Effectiveness and Safety of Upadacitinib Versus Risankizumab for Crohn's Disease.

Pubmed   Journal   ReadQx 

Single Center Audit of the Diagnosis of Bile Acid Diarrhea Based on Fasting Serum 7αC4 and Single Stool Primary Bile Acid Content.

Pubmed   Journal   ReadQx 

Endosc Int Open

Non-insufflation endoscopic intermuscular dissection in the management of a rectal neuroendocrine tumor.

Pubmed   Journal   ReadQx 

Novel application of multi-loop traction device and threaded clip in gastric endoscopic submucosal dissection.

Pubmed   Journal   ReadQx 

Endoscopy

A giant cerebriform submucosal lipoma extending from the gastric body to the duodenal bulb: a case report.

Pubmed   Journal   ReadQx   PMC

A novel peroral cholangioscopy of gallbladder carcinosarcoma: a case report.

Pubmed   Journal   ReadQx 

A rare cause of posttraumatic esophageal perforation successfully treated with a new vacuum stent.

Pubmed   Journal   ReadQx   PMC

Delayed intra-abdominal bleeding after endoscopic resection of an inverted appendiceal lesion.

Pubmed   Journal   ReadQx   PMC

Dental floss traction-assisted precut sphincterotomy for difficult biliary cannulation in elongated papilla.

Pubmed   Journal   ReadQx 

Diagnostic endoscopic submucosal dissection for a reddish depressed gastric lesion: morphological and pathological upgrading.

Pubmed   Journal   ReadQx 

Double-balloon endoscopy-assisted peroral pancreatoscopy using a novel slim cholangiopancreatoscope for the diagnosis of pancreatic duct stricture in surgically altered anatomy.

Pubmed   Journal   ReadQx   PMC

Endoscopic closure of a congenital tracheo-esophageal fistula using a through-the-scope suturing device in a young boy.

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Endoscopic hepaticogastrostomy combined with antegrade stent deployment using a multi-hole stent with a 5.9-Fr stent delivery system for patients with complete situs inversus.

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Endoscopic intermuscular dissection for a duodenal neuroendocrine tumor using saline-immersion therapeutic endoscopy.

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Endoscopic ultrasound-guided antegrade biliary intervention for choledocholithiasis in total gastrectomy with Roux-en-Y anatomy.

Pubmed   Journal   ReadQx   PMC

Endoscopic ultrasound-guided fine-needle biopsy of pancreatic hepatoid adenocarcinoma.

Pubmed   Journal   ReadQx   PMC

Focal endoscopic intermuscular dissection guided by the pocket-detection method for radical excision of early T2 rectal cancer.

Pubmed   Journal   ReadQx   PMC

Intraoperative closure of a large colonic perforation using dual adjustable instrument and channel endoscopy.

Pubmed   Journal   ReadQx   PMC

Muscle inversion closure technique with novel clips minimizes submucosal dead space after colorectal endoscopic submucosal dissection.

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Preoperative virtual reality-guidance for safe gastric endoscopic full-thickness resection with a suitable closure strategy.

Pubmed   Journal   ReadQx   PMC

Radiation-free extraction of intrahepatic biliary ascariasis in a pregnant patient using peroral cholangioscopy: a case report.

Pubmed   Journal   ReadQx   PMC

Radiofrequency ablation for anti-gastroesophageal reflux under direct vision via nasal endoscopy.

Pubmed   Journal   ReadQx   PMC

Scope withdrawal technique to prevent transesophageal puncture during endoscopic ultrasound-guided hepaticogastrostomy.

Pubmed   Journal   ReadQx   PMC

Two devices in one channel procedure for difficult cannulation due to periampullary diverticulum using a new duodenoscope.

Pubmed   Journal   ReadQx   PMC

Gastroenterology

Impact of Behavioral Interventions on Fecal Immunochemical Testing Uptake from a Randomized Trial.

Pubmed   Journal   ReadQx 

Scrotal swelling in a patient with Crohn's disease: More than meets the eye.

Pubmed   Journal   ReadQx 

Serotonin's New Frontier: SSRIs Unveiled as Cancer Immunotherapy.

Pubmed   Journal   ReadQx 

Gut

New player in inflammation-driver liver carcinogenesis: pirin on fire!

Pubmed   Journal   ReadQx 

Hepatology

Peripheral blood Foxp3-High tregs: A novel prognostic biomarker in hepatocellular carcinoma.

Pubmed   Journal   ReadQx 

Reply: Clarifying the impact of response criteria and locoregional therapy on complete response outcomes in patients with hepatocellular carcinoma following immunotherapy.

Pubmed   Journal   ReadQx 

J Hepatol

Hepatic stellate cells regulate multiple aspects of hepatocyte function in health and disease.

Pubmed   Journal   ReadQx 


Letters&Replies

Letters to the editors and authors’ replies

Aliment Pharmacol Ther

Editorial: Bridging the Gap Between Evidence and Practice in Hepatitis B Virus Related Hepatocellular Carcinoma Prevention-Authors' Reply.

Pubmed   Journal   ReadQx 

Clin Gastroenterol Hepatol

Assessing early post-TIPS hepatic encephalopathy and survival: What key factors remain unaddressed?

Pubmed   Journal   ReadQx 

Expanding Access to Colorectal Cancer Screening with Digital Tools.

Pubmed   Journal   ReadQx 

GEMA-AI: artificial intelligence for a more rational and equitable access to liver transplantation.

Pubmed   Journal   ReadQx 

Endosc Int Open

Exegesis on using a customized GPT to provide guideline-based recommendations for the management of pancreatic cystic lesions.

Pubmed   Journal   ReadQx   PMC

Gastroenterology

Comments on "Postoperative Endoscopic Outcomes in the MESOCOLIC Trial Investigating Mesenteric-Based Surgery for Crohn's Disease".

Pubmed   Journal   ReadQx 

Describing rates of post-colonoscopy colorectal cancer: potential risks as well as benefits?

Pubmed   Journal   ReadQx 

Mechanistic Insights into Prucalopride's Role in IBS Treatment: Schwann-like Enteric Glial Cells as Therapeutic Targets.

Pubmed   Journal   ReadQx 

J Hepatol

Reframing The Spectrum of Steatotic Liver Disease as a Dynamic Concept.

Pubmed   Journal   ReadQx 

The role of liver biopsy in diagnosing patients with autoimmune hepatitis- it can be acceptable to skip!

Pubmed   Journal   ReadQx 

J Neurogastroenterol Motil

From Trials to Practice: Exploring the Clinical Value of Potassium-competitive Acid Blockers

Pubmed   Journal   ReadQx 

The Value of 3-Dimensional Anorectal Manometry in the Evaluation of Obstetric Anal Sphincter Injuries.

Pubmed   Journal   ReadQx